Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics
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چکیده
منابع مشابه
Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics
The assessment of oocyte quality in human in vitro fertilization (IVF) is getting increasing attention from embryologists. Oocyte selection and the identification of the best oocytes, in fact, would help to limit embryo overproduction and to improve the results of oocyte cryostorage programs. Follicular fluid (FF) is easily available during oocyte pick-up and theorically represents an optimal s...
متن کاملFollicular fluid markers of oocyte developmental potential.
BACKGROUND Concentrations of certain substances in follicular fluid (FF) are related to fertilization outcome and early post-fertilization development. The study aim was to identify FF markers with which to predict embryo implantation potential. METHODS Concentrations of selected hormones, cytokines and growth factors in individual FF samples obtained during assisted reproduction treatment we...
متن کاملO-26: Effects of Recombinant-LH Supplementation on The Proteomic Profile of Follicular Fluid from Poor Responder Patients: Focus on Follicular Growth Factors and Oocyte Maturity Markers
Background Poor and fragmentary data was available regarding the effects of recombinant-LH (r-LH) in in-vitro granulosa and theca cells of human origin. No data was available from in vivo studies regarding the effects of r-LH supplementation on SCF,EGF,ERK-1/2 and AKT-1 pathways in the follicular fluid of older-poor-responder women undergoing IVF cycle. Evidence from in-vitro and animal studies...
متن کاملthe influence of corpus luteum on follicular fluid composition from different size follicles and their relationship to serum concentrations in sanjabi ewes
the aim of the present study was to determine the in?uence of presence or absence of corpus luteum (cl) on hormonal and metabolites composition of follicular ?uid (ff) harvested from different sized follicles and its relationship with blood serum concentrations in sanjabi ewes. ovaries and blood samples were collected from 60 clinically healthy adult ewes (sanjabi breed) 1–3 years of age in dio...
Metabolomics: approaches to assessing oocyte and embryo quality.
Morphological evaluation remains the primary method of embryo assessment during IVF cycles, but its modest predictive power and inherent inter- and intra-observer variability limits its value. Low-molecular weight metabolites represent the end products of cell regulatory processes and therefore reveal the response of biological systems to a variety of genetic, nutrient or environmental influenc...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2009
ISSN: 1477-7827
DOI: 10.1186/1477-7827-7-40